Man’s Man: High Testosterone, Low Immunity

  • 1 minute read
  • Wellbeing
  • Self Care
  • Dr. Jatin Bhide

A 2013 study, published in the ‘Proceedings of the National Academy of Sciences’, from Stanford’s Institute for Immunity, Transplantation and Infection, says that men are more susceptible to bacterial, viral, fungal and parasitic infection than women and that men’s immune systems don’t respond as strongly as women’s to vaccinations against many infectious diseases.

This is because testosterone seems to shrink immune responsiveness.

The Stanford study found that men with higher testosterone levels had a weaker response while women and men with low levels of testosterone did better.

The researchers explained that testosterone appears to interact with a particular set of genes called Module 52 genes. This interaction may hinder immune response.

Says another study, published in the journal ‘Andrology’ in 2020, “Men have a basal, biological predisposition to get sick from COVID-19, either from their higher plasma testosterone levels compared with women or from age-related low testosterone levels, which, being an important parameter of frailty, could result in severe and potentially fatal forms of COVID-19 infection among men.”

So, testosterone can modulate the immune system. But, gentlemen, here are a couple of ways to strengthen your immunity:

  • Eat more fermented foods or take a high-quality probiotic supplement
  • Get your vitamin D levels Research has shown vitamin D supplementation can help boost immunity
  • Get in more Include nuts, seeds and cacao in your diet
  • Manage stress
  • Get enough exercise daily.

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